Seminars in Colon & Rectal Surgery
Volume 19, Issue 1 , Pages 9-15 , March 2008

The Role of Postoperative Analgesia on Outcomes in Colorectal Surgery

  • Claudia Hriesik, MD, PhD
  • ,
  • Massarat Zutshi, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to: Massarat Zutshi, MD, Cleveland Clinic Foundation, A-30 Department of Colorectal Cancer, 9500 Euclid Avenue, Cleveland, OH 44195.

References 

  1. Kehlet H, Buchler MW, Beart RW, et al. Care after colonic operation—is it evidence-based? (Results from a multinational survey in Europe and the United States). J Am Coll Surg. 2006;202(1):45–54
  2. Andersen J, Hjort-Jakobsen D, Christiansen PS, et al. Readmission rates after a planned hospital stay of 2 versus 3 days in fast-track colonic surgery. Br J Surg. 2007;94(7):890–893
  3. Joshi GP. Multimodal analgesia techniques and postoperative rehabilitation. Anesthesiol Clin North America. 2005;23(1):185–202
  4. Liu SS, Carpenter RL, Mackey DC, et al. Effects of perioperative analgesic technique on rate of recovery after colon surgery. Anesthesiology. 1995;83(4):757–765
  5. Hatakeyama Y, Nishi K, Ohno T, et al. [Studies on cultivation of Papaver somniferum L. and extraction of the alkaloids. L. and extraction of the alkaloids I. Effect of planting density of the growth and yield]. Eisei Shikenjo Hokoku. 1974;49(92):32–39
  6. Kosterlitz HW, Corbett AD, Paterson SJ. Opioid receptors and ligands. NIDA Res Monogr. 1989;95:159–166
  7. Steinberg RB, Liu SS, Wu CL, et al. Comparison of ropivacaine-fentanyl patient-controlled epidural analgesia with morphine intravenous patient-controlled analgesia for perioperative analgesia and recovery after open colon surgery. J Clin Anesth. 2002;14(8):571–577
  8. Moore A, Collins S, Carroll D, et al. Paracetamol with and without codeine in acute pain: a quantitative systematic review. Pain. 1997;70(2-3):193–201
  9. Holmer Pettersson P, Owall A, Jakobsson J. Early bioavailability of paracetamol after oral or intravenous administration. Acta Anaesthesiol Scand. 2004;48(7):867–870
  10. Elia N, Lysakowski C, Tramer MR. Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? (Meta-analyses of randomized trials). Anesthesiology. 2005;103(6):1296–1304
  11. Romsing J, Moiniche S. A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain. Acta Anaesthesiol Scand. 2004;48(5):525–546
  12. Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA. 2001;286(8):954–959
  13. Schlachta CM, Burpee SE, Fernandez C, et al. Optimizing recovery after laparoscopic colon surgery (ORAL-CS): effect of intravenous Ketorolac on length of hospital stay. Surg Endosc. 2007;21:2212–2219
  14. Wong CS, Liaw WJ, Tung CS, et al. Ketamine potentiates analgesic effect of morphine in postoperative epidural pain control. Reg Anesth 21. 1996;(6):534–541
  15. Kehlet H. Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth. 1997;78(5):606–617
  16. Goyagi T, Tanaka M, Nishikawa T. Oral clonidine premedication enhances postoperative analgesia by epidural morphine. Anesth Analg. 1999;89(6):1487–1491
  17. Kehlet H, Holte K. Effect of postoperative analgesia on surgical outcome. Br J Anaesth. 2001;87(1):62–72
  18. Stensethz R, Bjella L, Berg EM, et al. Thoracic epidural analgesia in aortocoronary bypass surgery II: effects on the endocrine metabolic response. Acta Anaesthesiol Scand. 1994;38(8):834–839
  19. Horlocker TT. What’s a nice patient like you doing with a complication like this? (Diagnosis, prognosis and prevention of spinal hematoma). Can J Anaesth. 2004;51(6):527–534
  20. Wysowski DK, Talarico L, Bacsanyi J, et al. Spinal and epidural hematoma and low-molecular-weight heparin. N Engl J Med. 1998;338(24):1774–1775
  21. Schroeder TH, Krueger WA, Neeser E, et al. Spinal epidural abscess—a rare complication after epidural analgesia for labour and delivery. Br J Anaesth. 2004;92(6):896–898
  22. Groen RJ, Ponssen H. The spontaneous spinal epidural hematoma (A study of the etiology). J Neurol Sci. 1990;98(2-3):121–138
  23. Kost-Byerly S, Tobin JR, Greenberg RS, et al. Bacterial colonization and infection rate of continuous epidural catheters in children. Anesth Analg. 1998;86(4):712–716
  24. McNeely JK, Farber NE, Rusy LM, et al. Epidural analgesia improves outcome following pediatric fundoplications (A retrospective analysis). Reg Anesth. 1997;22(1):16–23
  25. Wang LP, Hauerberg J, Schmidt JF. Incidence of spinal epidural abscess after epidural analgesia: a national 1-year survey. Anesthesiology. 1999;91(6):1928–1936
  26. Ready LB, Loper KA, Nessly M, et al. Postoperative epidural morphine is safe on surgical wards. Anesthesiology. 1991;75(3):452–456
  27. Lema MJ. Monitoring epidural local anesthetic action during the postoperative period. Reg Anesth. 1996;21(suppl 6):94–99
  28. Mulroy MF. Systemic toxicity and cardiotoxicity from local anesthetics: incidence and preventive measures. Reg Anesth Pain Med. 2002;27(6):556–561
  29. Tzeng JI, Chu KS, Ho ST, et al. Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control. Can J Anaesth. 2003;50(10):1023–1026
  30. Shah JL. Lesson of the week: postoperative pressure sores after epidural anaesthesia. BMJ. 2000;321(7266):941–942
  31. Liu YJ, Chin KW, Su JY, et al. The experience of two-epidural-catheter for painless labor. Acta Anaesthesiol Sin. 1994;32(4):251–254
  32. Burstal R, Wegener F, Hayes C, et al. Epidural analgesia: prospective audit of 1062 patients. Anaesth Intensive Care. 1998;26(2):165–172
  33. Burstal R, Wegener F, Hayes C, et al. Subcutaneous tunnelling of epidural catheters for postoperative analgesia to prevent accidental dislodgement: a randomized controlled trial. Anaesth Intensive Care. 1998;26(2):147–151
  34. Kehlet H, Dahl JB. Anaesthesia, surgery, and challenges in postoperative recovery. Lancet. 2003;362(9399):1921–1928
  35. Holte K, Kehlet H. Postoperative ileus: a preventable event. Br J Surg. 2000;87(11):1480–1493
  36. Neudecker J, Schwenk W, Junghans T, et al. Randomized controlled trial to examine the influence of thoracic epidural analgesia on postoperative ileus after laparoscopic sigmoid resection. Br J Surg. 1999;86(10):1292–1295
  37. Jorgensen H, Wetterslev J, Moiniche S, et al. Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. Cochrane Database Syst Rev. 2000;4:CD001893
  38. Nishimori M, Ballantyne JC, Low JH. Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery. Cochrane Database Syst Rev. 2006;3:CD005059
  39. Liu SS, Richman JM, Thirlby RC, et al. Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trials. J Am Coll Surg. 2006;203(6):914–932
  40. Basse L, Hjort Jakobsen D, Billesbolle P, et al. A clinical pathway to accelerate recovery after colonic resection. Ann Surg. 2000;232(1):51–57
  41. Delaney CP, Fazio VW, Senagore AJ, et al. ‘Fast track’ postoperative management protocol for patients with high co-morbidity undergoing complex abdominal and pelvic colorectal surgery. Br J Surg. 2001;88(11):1533–1538
  42. Spatz H, Zulke C, Beham A, et al. [“Fast-Track” for laparoscopic-assisted rectum resection—what can be achieved? First results of a feasibility study]. Zentralbl Chir. 2006;131(5):383–387
  43. Kehlet H, Gray AW, Bonnet F, et al. A procedure-specific systematic review and consensus recommendations for postoperative analgesia following laparoscopic cholecystectomy. Surg Endosc. 2005;19(10):1396–1415
  44. Kehlet H. Procedure-specific postoperative pain management. Anesthesiol Clin North Am. 2005;23(1):203–210
  45. Joshi GP, Kehlet H, Rawal N. Evidence-based guidelines for postoperative pain management. Reg Anesth Pain Med. 2007;32(2):173
  46. Hahnenkamp K, Theilmeier G, Van Aken HK, et al. The effects of local anesthetics on perioperative coagulation, inflammation, and microcirculation. Anesth Analg. 2002;94(6):1441–1447
  47. Hollmann MW, Durieux ME. Local anesthetics and the inflammatory response: a new therapeutic indication?. Anesthesiology. 2000;93(3):858–875
  48. Liu SS, Wu CL. Effect of postoperative analgesia on major postoperative complications: a systematic update of the evidence. Anesth Analg. 2007;104(3):689–702
  49. Richman JM, Liu SS, Courpas G, et al. Does continuous peripheral nerve block provide superior pain control to opioids? (A meta-analysis). Anesth Analg. 2006;102(1):248–257
  50. Moiniche S, Kehlet H, Dahl JB. A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief: the role of timing of analgesia. Anesthesiology. 2002;96(3):725–741
  51. Woolf CJ, Chong MS. Preemptive analgesia—treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg. 1993;77(2):362–379
  52. Katz J, Kavanagh BP, Sandler AN, et al. Preemptive analgesia (Clinical evidence of neuroplasticity contributing to postoperative pain). Anesthesiology. 1992;77(3):439–446
  53. Gottschalk A, Smith DS, Jobes DR, et al. Preemptive epidural analgesia and recovery from radical prostatectomy: a randomized controlled trial. JAMA. 1998;279(14):1076–1082
  54. Kehlet H. Epidural analgesia and recovery after abdominal surgery. Am J Surg. 2007;193(2):291–292291; author reply
  55. Faynsod M, Stamos MJ, Arnell T, et al. A case-control study of laparoscopic versus open sigmoid colectomy for diverticulitis. Am Surg. 2000;66(9):841–843
  56. Heidi Nelson MD, Danie PD, Sargent J, et al. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 2004;350(20):2050–2059
  57. Senagore AJ, Delaney CP. A critical analysis of laparoscopic colectomy at a single institution: lessons learned after 1000 cases. Am J Surg. 2006;191(3):377–380
  58. Basse L, Jacobsen DH, Billesbolle P, et al. Colostomy closure after Hartmann’s procedure with fast-track rehabilitation. Dis Colon Rectum. 2002;45(12):1661–1664
  59. Zutshi M, Delaney CP, Senagore AJ, et al. Shorter hospital stay associated with fast-track postoperative care pathways and laparoscopic intestinal resection are not associated with increased physical activity. Colorectal Dis. 2004;6(6):477–480
  60. Junghans T, Raue W, Haase O, et al. [Value of laparoscopic surgery in elective colorectal surgery with “fast-track”-rehabilitation]. Zentralbl Chir. 2006;131(4):298–303
  61. Marusch F, Koch A, Schmidt U, et al. [“Colon-/rectal carcinoma” prospective studies as comprehensive surgical quality assurance]. Chirurg. 2002;73(2):138–145discussion 145-146
  62. Marusch F, Gastinger I, Schneider C, et al. Experience as a factor influencing the indications for laparoscopic colorectal surgery and the results. Surg Endosc. 2001;15(2):116–120
  63. Marusch F, Gastinger I, Schneider C, et al. Importance of conversion for results obtained with laparoscopic colorectal surgery. Dis Colon Rectum. 2001;44(2):207–214discussion 214-216
  64. Kiran RP, Pokala N, Dudrick SJ. Long-term outcome after operative intervention for rectal cancer in patients aged over 80 years: analysis of 9,501 patients. Dis Colon Rectum. 2007;50(5):604–610

PII: S1043-1489(08)00004-3

doi: 10.1053/j.scrs.2008.01.003

Seminars in Colon & Rectal Surgery
Volume 19, Issue 1 , Pages 9-15 , March 2008